Identification of a Critical Residue in the Transmembrane Domain 2 of Tachykinin Neurokinin 3 Receptor Affecting the Dissociation Kinetics and Antagonism Mode of Osanetant (SR 142801) and Piperidine-Based Structures-Reference-Cited by-同舟云学术

Identification of a Critical Residue in the Transmembrane Domain 2 of Tachykinin Neurokinin 3 Receptor Affecting the Dissociation Kinetics and Antagonism Mode of Osanetant (SR 142801) and Piperidine-Based Structures

Published:2009-10-09 Issue:22 Volume:52 Page:7103-7112
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Malherbe Pari¹,Kratzeisen Claudia¹,Marcuz Anne¹,Zenner Marie-Thérèse¹,Nettekoven Matthias H.²,Ratni Hasane²,Wettstein Joseph G.¹,Bissantz Caterina²

Affiliation:

1. Discovery Research CNS

2. Chemistry

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900948q

Reference39 articles.

1. Guide to Receptors and Channels (GRAC), 3rd edition

2. Tachykinins and Tachykinin Receptors: Structure and Activity Relationships

3. The Tachykinin Peptide Family

4. Detailed distribution of Neurokinin 3 receptors in the rat, guinea pig and gerbil brain: a comparative autoradiographic study

5. Distribution and pharmacological characterization of primate NK-1 and NK-3 tachykinin receptors in the central nervous system of the rhesus monkey

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