Histone Deacetylase (HDAC) Inhibitors with a Novel Connecting Unit Linker Region Reveal a Selectivity Profile for HDAC4 and HDAC5 with Improved Activity against Chemoresistant Cancer Cells-Reference-Cited by-同舟云学术

Histone Deacetylase (HDAC) Inhibitors with a Novel Connecting Unit Linker Region Reveal a Selectivity Profile for HDAC4 and HDAC5 with Improved Activity against Chemoresistant Cancer Cells

Published:2013-01-08 Issue:2 Volume:56 Page:427-436
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Marek Linda¹,Hamacher Alexandra¹,Hansen Finn K.¹,Kuna Krystina¹,Gohlke Holger¹,Kassack Matthias U.¹,Kurz Thomas¹

Affiliation:

1. Institut für Pharmazeutische und Medizinische Chemie, Heinrich Heine Universität, Universitätsstrasse 1, 40225 Düsseldorf, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm301254q

Reference39 articles.

1. Epigenetics—An Epicenter of Gene Regulation: Histones and Histone-Modifying Enzymes

2. Histone Deacetylase Inhibitors: From Bench to Clinic

3. Histone deacetylase inhibitors that target tubulin

4. Inside HDAC with HDAC inhibitors

5. HDAC family: What are the cancer relevant targets?

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