Discovery of a Chemical Modification by Citric Acid in a Recombinant Monoclonal Antibody-Reference-Cited by-同舟云学术

Discovery of a Chemical Modification by Citric Acid in a Recombinant Monoclonal Antibody

Published:2014-08-27 Issue:18 Volume:86 Page:8932-8936
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Chumsae Chris¹²,Zhou Liqiang Lisa¹,Shen Yang¹,Wohlgemuth Jessica³,Fung Emma⁴,Burton Randall¹,Radziejewski Czeslaw¹,Zhou Zhaohui Sunny²

Affiliation:

1. Protein Analytics, Process Sciences, AbbVie Bioresearch Center, Worcester, Massachusetts 01605, United States

2. Barnett Institute of Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115-5000, United States

3. NBE Analytical Research and Development, AbbVie, Ludwigshafen 67061, Germany

4. Biologics, AbbVie Bioresearch Center, Worcester, Massachusetts 01605, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac502179m

Reference65 articles.

1. One cell–one immunoglobin. Origin of limited heterogeneity of myeloma proteins

2. Heterogeneity of Monoclonal Antibodies

3. Stability of Protein Pharmaceuticals: An Update

4. Heterogeneity of Monoclonal Antibodies Revealed by Charge-Sensitive Methods

5. Mass spectrometric analysis of proteins

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