Using In Vitro and Machine Learning Approaches to Determine Species-Specific Dioxin-like Potency and Congener-Specific Relative Sensitivity among Birds for Brominated Dioxin Analogues

Author:

Zhang Rui1ORCID,Wu Qiuxuan1,Qi Xiaoyi23,Wang Xiaoxiang45,Zhang Xuesheng6,Song Chao78,Peng Ying9ORCID,Crump Doug10,Zhang Xiaowei11

Affiliation:

1. School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China

2. Department of Gynecology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250021, China

3. Department of Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China

4. State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution Control, Guangdong Provincial Key Laboratory of Soil and Groundwater Pollution Control, School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China

5. Yuanshang Technology Co., Ltd., Shenzhen 518126, China

6. School of Resources and Environmental Engineering, Anhui University, Hefei 230601, China

7. Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, China

8. Laboratory of Quality & Safety Risk Assessment for Aquatic Products on Environmental Factors (Wuxi), Ministry of Agriculture, Wuxi 214081, China

9. Research and Development Center for Watershed Environmental Eco-Engineering, Beijing Normal University, Zhuhai 519087, China

10. Ecotoxicology and Wildlife Health Division, Environment and Climate Change Canada, National Wildlife Research Centre, Carleton University, Ottawa K1A 0H3, Canada

11. State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Nanjing University, Nanjing 210023, China

Funder

Guangdong Science and Technology Department

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Publisher

American Chemical Society (ACS)

Subject

Environmental Chemistry,General Chemistry

Reference67 articles.

1. Polybrominated Dibenzo-p-Dioxins, Dibenzofurans, and Biphenyls: Inclusion in the Toxicity Equivalency Factor Concept for Dioxin-Like Compounds

2. Health effects of polybrominated dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs)

3. Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for Polybrominated Biphenyls and Polybrominated Diphenyl Ethers; U.S. Department of Health and Human Services, Public Health Service: Atlanta, GA. 2004, Available at: https://www.atsdr.cdc.gov/ToxProfiles/tp68.pdf (accessed on Aug 10, 2021).

4. Characterisation of chlorinated, brominated and mixed halogenated dioxins, furans and biphenyls as potent and as partial agonists of the Aryl hydrocarbon receptor

5. Polybrominated Biphenyl and Diphenylether Flame Retardants: Analysis, Toxicity, and Environmental Occurrence

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