A Novel Scalable Process to the GSK3β Inhibitor AZD8926 Based on a Heterocyclic Ziegler Coupling-Reference-Cited by-同舟云学术

A Novel Scalable Process to the GSK3β Inhibitor AZD8926 Based on a Heterocyclic Ziegler Coupling

Published:2013-04-08 Issue:4 Volume:17 Page:672-678
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Witt Anette¹,Teodorovic Peter¹,Linderberg Mats¹,Johansson Peter¹,Minidis Anna¹

Affiliation:

1. Pharmaceutical Development R&D, Chemical Science, AstraZeneca, S-151 85 Södertälje, Sweden

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op300365e

Reference27 articles.

1. GSK3β Signalling: Casting a Wide Net in Alzheimer’s Disease

2. Glycogen synthase kinase 3: a drug target for CNS therapies

3. Andersson, L.; Arzel, E.; Berg, S.; Burrows, J.; Hellberg, S.; Huerta, F.; Pedersen, T.; Rein, T.; Rotticci, D.; Staaf, K.; Turek, D.(Astrazeneca AB, Sweden). PCT Int. Appl. WO/2007/040440 A1, 2007.

4. 2-Trifluoromethylimidazole, 2,4,5-tris (trifluoromethyl)imidazole and related compounds

Cited by 18 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Diversification of Pharmaceutical Manufacturing Processes: Taking the Plunge into the Non-PGM Catalyst Pool;ACS Catalysis;2024-06-13

2. Large-Scale Amidations in Process Chemistry: Practical Considerations for Reagent Selection and Reaction Execution;Organic Process Research & Development;2022-06-07

3. Buchwald–Hartwig Amination;Name Reactions;2021

4. Development and Scale-Up of a Continuous Aerobic Oxidative Chan–Lam Coupling;Organic Process Research & Development;2019-06-21

5. A rhodium-catalyzed three-component reaction of arylisocyanides, trifluorodiazoethane, and activated methylene isocyanides or azomethine ylides: an efficient synthesis of trifluoroethyl-substituted imidazoles;Organic Chemistry Frontiers;2019