Subtype Polymorphisms Among HIV-1 Protease Variants Confer Altered Flap Conformations and Flexibility-Reference-Cited by-同舟云学术

Subtype Polymorphisms Among HIV-1 Protease Variants Confer Altered Flap Conformations and Flexibility

Published:2009-09-29 Issue:41 Volume:131 Page:14650-14651
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Kear Jamie L.¹,Blackburn Mandy E.¹,Veloro Angelo M.¹,Dunn Ben M.¹,Fanucci Gail E.¹

Affiliation:

1. Department of Chemistry, P.O. Box 117200, University of Florida, Gainesville, Florida 32611-7200, and Department of Biochemistry and Molecular Biology, University of Florida College of Medicine Health Science Center, Gainesville, Florida 32610

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja907088a

Reference24 articles.

1. An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection.

2. INHIBITORS OF HIV-1 PROTEASE: A Major Success of Structure-Assisted Drug Design

3. Analysis of HIV-1 CRF_01 A/E Protease Inhibitor Resistance: Structural Determinants for Maintaining Sensitivity and Developing Resistance to Atazanavir

4. Amplification of the Effects of Drug Resistance Mutations by Background Polymorphisms in HIV-1 Protease from African Subtypes

Cited by 40 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Natural Polymorphisms D60E and I62V Stabilize a Closed Conformation in HIV-1 Protease in the Absence of an Inhibitor or Substrate;Viruses;2024-02-02

2. Direct observation of negative cooperativity in a detoxification enzyme at the atomic level by Electron Paramagnetic Resonance spectroscopy and simulation;Protein Science;2023-09-15

3. Comprehending the Structure, Dynamics, and Mechanism of Action of Drug-Resistant HIV Protease;ACS OMEGA;2023

4. Comprehending the Structure, Dynamics, and Mechanism of Action of Drug-Resistant HIV Protease;ACS Omega;2023-03-07

5. Genetic Diversity and Low Therapeutic Impact of Variant-Specific Markers in HIV-1 Pol Proteins;Frontiers in Microbiology;2022-07-14