1. Department of Cellular and Molecular Physiology and Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, American Health Foundation Cancer Center, Institute for Cancer Prevention, Valhalla, New York 10595, Laboratory of Comparative Carcinogenesis, National Cancer Institute at Frederick, Frederick, Maryland 21702, and College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55455