Predicting Adult Fish Acute Lethality with the Zebrafish Embryo: Relevance of Test Duration, Endpoints, Compound Properties, and Exposure Concentration Analysis

Author:

Knöbel Melanie1,Busser Frans J. M.2,Rico-Rico Ángeles2,Kramer Nynke I.2,Hermens Joop L. M.2,Hafner Christoph3,Tanneberger Katrin1,Schirmer Kristin145,Scholz Stefan6

Affiliation:

1. Eawag-Swiss Federal Institute of Aquatic Science and Technology, Department of Environmental Toxicology, 8600 Dübendorf, Switzerland

2. Institute for Risk Assessment Sciences, Toxicology Division, Utrecht University, 3508 TD Utrecht, The Netherlands

3. Hydrotox GmbH, 79111 Freiburg, Germany

4. ETH Zürich, Department of Environmental Systems Science, 8092 Zürich, Switzerland

5. EPF Lausanne, School of Architecture, Civil and Environmental Engineering, 1015 Lausanne, Switzerland

6. UFZ-Helmholtz Centre for Environmental Research, Department of Bioanalytical Ecotoxicology, 04318 Leipzig, Germany

Publisher

American Chemical Society (ACS)

Subject

Environmental Chemistry,General Chemistry

Reference47 articles.

1. Regulatory aspects on the use of fish embryos in environmental toxicology

2. The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research

3. Canada Gazette. Canadian Environmental Protection Act, 1999; 22 (3 Part III),http://www.ec.gc.ca/lcpe-cepa/default.asp?lang=En&n=24374285-1(accessed February 10, 2012).

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