Arylsulfonamidothiazoles as a New Class of Potential Antidiabetic Drugs. Discovery of Potent and Selective Inhibitors of the 11β-Hydroxysteroid Dehydrogenase Type 1

Author:

Barf Tjeerd1,Vallgårda Jerk1,Emond Rikard1,Häggström Charlotta1,Kurz Guido1,Nygren Alf1,Larwood Vivienne1,Mosialou Erifili1,Axelsson Kent1,Olsson Rolf1,Engblom Lars1,Edling Naimie1,Rönquist-Nii Yuko1,Öhman Birgitta1,Alberts Peteris1,Abrahmsén Lars1

Affiliation:

1. Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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