Chemistry and Biology of Cylindrols: Novel Inhibitors of Ras Farnesyl-Protein Transferase from Cylindrocarpon lucidum-Reference-Cited by-同舟云学术

Chemistry and Biology of Cylindrols: Novel Inhibitors of Ras Farnesyl-Protein Transferase from Cylindrocarpon lucidum

Published:1996-01-01 Issue:22 Volume:61 Page:7727-7737
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Singh Sheo B.¹,Ball Richard G.¹,Bills Gerald F.¹,Cascales Carmen¹,Gibbs Jackson B.¹,Goetz Michael A.¹,Hoogsteen Karst¹,Jenkins Rosalind G.¹,Liesch Jerrold M.¹,Lingham Russell B.¹,Silverman Keith C.¹,Zink Deborah L.¹

Affiliation:

1. Merck Research Laboratories, P.O. Box 2000 Rahway, New Jersey 07065 and West Point, Pennsylvania 19486 and Centro de Investigación Básica, Merck Sharp & Dohme de España S.A., Josefa Valcárcel 38, 28027, Madrid, Spain

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo961074p

Reference51 articles.

1. ras GENES

2. Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

3. Polyisoprenylation of Ras in vitro by a farnesyl-protein transferase.

4. Identification and preliminary characterization of protein-cysteine farnesyltransferase.

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