Gain of Function Mutagenesis of the Erythromycin Polyketide Synthase. 2. Engineered Biosynthesis of an Eight-Membered Ring Tetraketide Lactone-Reference-Cited by-同舟云学术

Gain of Function Mutagenesis of the Erythromycin Polyketide Synthase. 2. Engineered Biosynthesis of an Eight-Membered Ring Tetraketide Lactone

Published:1997-11-01 Issue:46 Volume:119 Page:11339-11340
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Kao Camilla M.¹,McPherson Michael¹,McDaniel Robert N.¹,Fu Hong¹,Cane David E.¹,Khosla Chaitan¹

Affiliation:

1. Departments of Chemical Engineering, Chemistry and Biochemistry, Stanford University Stanford, California 94305-5025 Department of Chemistry, Box H, Brown University Providence, Rhode Island 02912 KOSAN Biosciences, Inc., 1450 Rollins Road Burlingame, California 94010

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja972609e

Reference25 articles.

1. POLYKETIDE SYNTHESIS: Prospects for Hybrid Antibiotics

2. Repositioning of a Domain in a Modular Polyketide Synthase to Promote Specific Chain Cleavage

Cited by 90 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Substrate Trapping in Polyketide Synthase Thioesterase Domains: Structural Basis for Macrolactone Formation;ACS Catalysis;2024-08-06

2. Substrate Trapping in Polyketide Synthase Thioesterase Domains: Structural Basis for Macrolactone Formation;2024-06-20

3. Thioesterases as tools for chemoenzymatic synthesis of macrolactones;Chemical Communications;2024

4. Total synthesis of LC-KA05, the proposed structure of LC-KA05-2, and 2,18-seco-lankacidinol B: A quest to revisit lankacidin biosynthesis;Tetrahedron;2021-05

5. A Polyketide Cyclase That Forms Medium-Ring Lactones;Journal of the American Chemical Society;2020-12-22