Substrate Trapping in Polyketide Synthase Thioesterase Domains: Structural Basis for Macrolactone Formation-Reference-Cited by-同舟云学术

Substrate Trapping in Polyketide Synthase Thioesterase Domains: Structural Basis for Macrolactone Formation

Published:2024-08-06 Issue:16 Volume:14 Page:12551-12563
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

McCullough Tyler M.¹²,Choudhary Vishakha¹²^ORCID,Akey David L.¹,Skiba Meredith A.¹²,Bernard Steffen M.¹³,Kittendorf Jeffrey D.¹,Schmidt Jennifer J.¹,Sherman David H.¹⁴⁵⁶^ORCID,Smith Janet L.¹²^ORCID

Affiliation:

1. Life Sciences Institute, Mary Sue Coleman Hall, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, Michigan 48109-2216, United States

2. Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109-0600, United States

3. Program in Chemical Biology, Mary Sue Coleman Hall, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, Michigan 48109-2216, United States

4. Department of Medicinal Chemistry, University of Michigan College of Pharmacy, Ann Arbor, Michigan 48109-1065, United States

5. Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109-1055, United States

6. Department of Microbiology & Immunology, University of Michigan Medical School, Ann Arbor, Michigan 48109-5632, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute of General Medical Sciences

Life Sciences Institute, University of Michigan

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acscatal.4c03637

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