Novel and Potent Inhibitors of 5-Lipoxygenase Product Synthesis Based on the Structure of Pirinixic Acid-Reference-Cited by-同舟云学术

Novel and Potent Inhibitors of 5-Lipoxygenase Product Synthesis Based on the Structure of Pirinixic Acid

Published:2008-08-19 Issue:17 Volume:51 Page:5449-5453
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Werz Oliver¹,Greiner Christine¹,Koeberle Andreas¹,Hoernig Christina¹,George Sven¹,Popescu Laura¹,Syha Ivonne¹,Schubert-Zsilavecz Manfred¹,Steinhilber Dieter¹

Affiliation:

1. Department of Pharmaceutical Analytics, Pharmaceutical Institute, Eberhard-Karls-University Tuebingen, Auf der Morgenstelle 8, D-72076 Tuebingen, Germany, Institute of Pharmaceutical Chemistry/ZAFES, Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Strasse 9, D-60438 Frankfurt, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800588x

Reference23 articles.

1. Leukotrienes

2. Therapeutic options for 5-lipoxygenase inhibitors

3. 5-Lipoxygenase: regulation of expression and enzyme activity

4. Development of 5-lipoxygenase inhibitors—lessons from cellular enzyme regulation

5. The molecular mechanism of peroxisome proliferator action: a model for species differences and mechanistic risk assessment

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