Small Molecule Ghrelin Receptor Inverse Agonists and Antagonists-Reference-Cited by-同舟云学术

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Small Molecule Ghrelin Receptor Inverse Agonists and Antagonists

Published:2014-08-06 Issue:21 Volume:57 Page:8671-8691
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cameron Kimberly O.¹,Bhattacharya Samit K.¹,Loomis A. Katrina²

Affiliation:

1. Worldwide Medicinal Chemistry, Pfizer Worldwide Research and Development, 610 Main Street, Cambridge, Massachusetts 02139, United States

2. Pharmatherapeutics Precision Medicine, Pfizer Worldwide Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm5003183

Reference191 articles.

1. Ghrelin is a growth-hormone-releasing acylated peptide from stomach

2. IUPHAR Database.http://www.iuphar-db.org/DATABASE/ObjectDisplayForward?familyId=28&objectId=246&familyType=RECEPTOR.

3. Structure-Activity Relationships of a Synthetic Pentapeptide that Specifically Releases Growth Hormonein Vitro*

4. Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites

5. The Synergistic Effects of His-D-Trp-Ala-Trp-D-Phe- Lys-NH2on Growth Hormone (GH)-Releasing Factor- Stimulated GH Release and Intracellular Adenosine 3',5'-Monophosphate Accumulation in Rat Primary Pituitary Cell Culture

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1. Ghrelin receptor antagonist JMV2959 blunts cocaine and oxycodone drug-seeking, but not self-administration, in male rats;Frontiers in Pharmacology;2023-09-19

2. Design and characterization of a triazole-based growth hormone secretagogue receptor modulator inhibiting the glucoregulatory and feeding actions of ghrelin;Biochemical Pharmacology;2022-08

3. Advances in the Development of Nonpeptide Small Molecules Targeting Ghrelin Receptor;Journal of Medicinal Chemistry;2022-02-14

4. Ghrelin receptor agonist hexarelin attenuates antinociceptive tolerance to morphine in rats;Canadian Journal of Physiology and Pharmacology;2021-05

5. Pharmacology of Gut Hormone Mimetics for Obesity and Diabetes;Reference Module in Biomedical Sciences;2021

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