A Mechanistic Model for the Aziridine Aldehyde-Driven Macrocyclization of Peptides
Author:
Affiliation:
1. Department of Chemistry, Brock University, St. Catharines, Ontario L2S 3A1, Canada
2. Department of Chemistry, University of Toronto, Toronto, Ontario M5S 2J7, Canada
Funder
Natural Sciences and Engineering Research Council of Canada
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.8b01198
Reference23 articles.
1. Form and Function in Cyclic Peptide Natural Products: A Pharmacokinetic Perspective
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3. Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis
4. New peptide architectures through C–H activation stapling between tryptophan–phenylalanine/tyrosine residues
5. Zaretsky, S.; Yudin, A. K. In Topics in Heterocyclic Chemistry; Lubell, W., Ed. Springer: Berlin Heidelberg, 2015; pp 1–32.
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1. The Role of Attractive Non-Covalent Interactions in Peptide Macrocyclization;The Journal of Organic Chemistry;2024-01-13
2. Intramolecular Hydrogen Bonding Enables a Zwitterionic Mechanism for Macrocyclic Peptide Formation: Computational Mechanistic Studies of CyClick Chemistry;Angewandte Chemie International Edition;2023-08-17
3. Intramolecular Hydrogen Bonding Enables a Zwitterionic Mechanism for Macrocyclic Peptide Formation: Computational Mechanistic Studies of CyClick Chemistry;Angewandte Chemie;2023-08-17
4. Synthetic Tools that Enable Synthesis and Understanding of Bioactive Macrocycles;Synlett;2022-07-06
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