Identification of N-Oxide and Sulfoxide Functionalities in Protonated Drug Metabolites by Using Ion–Molecule Reactions Followed by Collisionally Activated Dissociation in a Linear Quadrupole Ion Trap Mass Spectrometer
Author:
Affiliation:
1. Purdue University, Department of Chemistry, West Lafayette, Indiana 47907, United States
2. AstraZeneca, Boston, Massachusetts 02130, United States
Funder
AstraZeneca
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.5b02409
Reference43 articles.
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4. Identification of 2-Aminothiazolobenzazepine Metabolites in Human, Rat, Dog, and Monkey Microsomes by Ion-Molecule Reactions in Linear Quadrupole Ion Trap Mass Spectrometry
5. A convenient chemical-microbial method for developing fluorinated pharmaceuticals
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