Solid-Phase Synthesis of Boranophosphate/Phosphorothioate/Phosphate Chimeric Oligonucleotides and Their Potential as Antisense Oligonucleotides
Author:
Affiliation:
1. Department of Medicinal and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
Funder
Japan Agency for Medical Research and Development
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.1c01812
Reference50 articles.
1. In vivoandin vitrostudies of antisense oligonucleotides – a review
2. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide.
3. Determination of the Role of the Human RNase H1 in the Pharmacology of DNA-like Antisense Drugs
4. Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
5. Antisense oligonucleotides: modifications and clinical trials
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3. New Molecular Technologies for Oligonucleotide Therapeutics-1: Properties and Synthesis of Boranophosphate DNAs;Handbook of Chemical Biology of Nucleic Acids;2023
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