In vivoandin vitrostudies of antisense oligonucleotides – a review-Reference-Cited by-同舟云学术

In vivoandin vitrostudies of antisense oligonucleotides – a review

Published:2020 Issue:57 Volume:10 Page:34501-34516
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kilanowska Anna¹²³⁴⁵^ORCID,Studzińska Sylwia¹²³⁴⁵

Affiliation:

1. Chair of Environmental Chemistry and Bioanalytics

2. Faculty of Chemistry

3. Nicolaus Copernicus University in Toruń

4. PL-87-100 Toruń

5. Poland

Abstract

Metabolism of ASOs is based on exonucleases degradation of subsequent nucleotides, with the activity of endonucleases in the case of some modifications.

Funder

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA04978F

Reference129 articles.

1. Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide.

2. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide.

3. Analysis of Antisense Oligonucleotides and Their Metabolites with the Use of Ion Pair Reversed-Phase Liquid Chromatography Coupled with Mass Spectrometry

4. Review on investigations of antisense oligonucleotides with the use of mass spectrometry

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