Improved Synthesis of a Cyclic Glutamine Analogue Used in Antiviral Agents Targeting 3C and 3CL Proteases Including SARS-CoV-2 Mpro
Author:
Affiliation:
1. Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada T6G 2G2
Funder
Canadian Institutes of Health Research
Canada Foundation for Innovation
Alberta Innovates
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.1c01299
Reference32 articles.
1. Broad-Spectrum Antivirals against 3C or 3C-Like Proteases of Picornaviruses, Noroviruses, and Coronaviruses
2. Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19
3. Human Coronavirus: Host-Pathogen Interaction
4. An Overview of Severe Acute Respiratory Syndrome–Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy
5. Origin and evolution of pathogenic coronaviruses
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