Access to Highly Enantioenriched Donepezil-like 1,4-Dihydropyridines as Promising Anti-Alzheimer Prodrug Candidates via Enantioselective Tsuji Allylation and Organocatalytic Aza-Ene-Type Domino Reactions
Author:
Affiliation:
1. Normandie Université, UNIROUEN, INSA Rouen, CNRS, COBRA, 76000 Rouen, France
2. VFP Therapies, R&D, 1 rue Tesnière, 76130 Mont Saint-Aignan, France
Funder
Agence Nationale de la Recherche
Universit? de Rouen
Centre National de la Recherche Scientifique
Institut National des Sciences Appliqu?es Rouen
R?gion Normandie
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.8b01442
Reference35 articles.
1. Synthesis, utility and medicinal importance of 1,2- & 1,4-dihydropyridines
2. Delivery of a Quaternary Pyridinium Salt Across the Blood-Brain Barrier by Its Dihydropyridine Derivative
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4. Strategies To Target Kyotorphin Analogues to the Brain
5. Retrometabolic drug design: Principles and recent developments
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