Regioselective Cycloaddition of Alkenes with <i>tert</i>-butyl Nitrite: A Cascade Approach to the Formation of Δ<sup>2</sup>-Isoxazolines-Reference-Cited by-同舟云学术

Regioselective Cycloaddition of Alkenes with tert-butyl Nitrite: A Cascade Approach to the Formation of Δ²-Isoxazolines

Published:2023-10-24 Issue:21 Volume:88 Page:15311-15317
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Liu Yi¹,Cao Juan¹,Zhang Mei¹,Zhang Zenghui¹,Xia Chengcai¹^ORCID,Guo Guili²,Wang Fugang¹

Affiliation:

1. Pharmacy College, Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, China

2. Department of Biochemistry and Molecule Biology, School of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250117, China

Funder

Shandong First Medical University

Medical and Health Science and Technology Development Project of Shandong Province

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c01815

Reference48 articles.

1. Critical modifications of the ISO-1 scaffold improve its potent inhibition of macrophage migration inhibitory factor (MIF) tautomerase activity

2. Recent Advances in Intramolecular Nitrile Oxide Cycloadditions in the Synthesis of 2-Isoxazolines

3. Synthesis and neuropharmacological evaluation of some new isoxazoline derivatives as antidepressant and anti-anxiety agents

4. Design, Synthesis, and Pharmacological Characterization of Novel Spirocyclic Quinuclidinyl-Δ2-Isoxazoline Derivatives as Potent and Selective Agonists of α7 Nicotinic Acetylcholine Receptors

5. Synthesis and evaluation of 4,5-dihydro-5-methylisoxazolin-5-carboxamide derivatives as VLA-4 antagonists

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