Solid-Phase Synthesis of Duocarmycin Analogues and the Effect of C-Terminal Substitution on Biological Activity-Reference-Cited by-同舟云学术

Solid-Phase Synthesis of Duocarmycin Analogues and the Effect of C-Terminal Substitution on Biological Activity

Published:2015-09-22 Issue:19 Volume:80 Page:9454-9467
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Stephenson Michael J.,Howell Lesley A.,O’Connell Maria A.,Fox Keith R.¹,Adcock Claire²,Kingston Jenny²,Sheldrake Helen³,Pors Klaus³,Collingwood Stephen P.²,Searcey Mark

Affiliation:

1. Centre for Biological Sciences, University of Southampton, Life Sciences Building 85, Southampton SO17 1BJ, United Kingdom

2. Novartis Institutes for Biomedical Research, Novartis Pharmaceuticals UK Limited, Horsham Research Centre, Wimblehurst Road, Horsham, West Sussex RH12 5AB, United Kingdom

3. Institute for Cancer Therapeutics, University of Bradford, Bradford, West Yorkshire BD7 1DP, United Kingdom

Funder

University of East Anglia

Novartis

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.5b01373

Reference63 articles.

1. Duocarmycin SA, a new antitumor antibiotic from Streptomyces sp.