Pyridine-Fused 2-Pyridones via Povarov and A3 Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding-Reference-Cited by-同舟云学术

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Pyridine-Fused 2-Pyridones via Povarov and A3 Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding

Published:2019-03-13 Issue:7 Volume:84 Page:3887-3903
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Singh Pardeep,Adolfsson Dan E.,Ådén Jörgen,Cairns Andrew G.,Bartens Christian¹,Brännström Kristoffer,Olofsson Anders,Almqvist Fredrik^ORCID

Affiliation:

1. Institute of Organic Chemistry and Center of Biomolecular Drug Research (BMWZ), Leibniz Universität Hannover, Schneiderberg 1b, Hannover 30167, Germany

Funder

Vetenskapsr?det

G?ran Gustafssons Stiftelse f?r Naturvetenskaplig och Medicinsk Forskning

Michael J. Fox Foundation for Parkinson's Research

Kempestiftelserna

Stiftelsen f?r?Strategisk Forskning

Knut och Alice Wallenbergs Stiftelse

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.8b03015

Reference44 articles.

1. Pilicides—small molecules targeting bacterial virulence

2. Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria

3. Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity

4. A 2-Pyridone-Amide Inhibitor Targets the Glucose Metabolism Pathway of Chlamydia trachomatis

5. Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity

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3. Solid state synthesis of bispyridyl-ferrocene conjugates with unusual site selective 1,4-Michael addition, as potential inhibitor and electrochemical probe for fibrillation in amyloidogenic protein;Journal of Molecular Structure;2023-02

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