Highly Diastereoselective Synthesis of 2,2-Disubstituted Cyclopentane-1,3-diols via Stepwise Ketone Reduction Enabling Concise Chirality Construction-Reference-Cited by-同舟云学术

Highly Diastereoselective Synthesis of 2,2-Disubstituted Cyclopentane-1,3-diols via Stepwise Ketone Reduction Enabling Concise Chirality Construction

Published:2020-07-15 Issue:15 Volume:85 Page:9599-9606
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Gong Jingyao¹²,Li Jianjiong²,Chen Xi²,Zhang Hongliu²,Zhu Liangyan²,Bu Dandan²,Wang Qin¹,Feng Jinhui²,Wu Qiaqing²,Zhu Dunming²^ORCID

Affiliation:

1. Department of Medicinal Chemistry, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan 646000, China

2. National Engineering Laboratory for Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 West seventh Avenue, Tianjin Airport Economic Area, Tianjin 300308, China

Funder

Ministry of Science and Technology of the People's Republic of China

Tianjin Science and Technology Committee

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.0c00851

Reference22 articles.

1. Total Synthesis and Biological Evaluation of 19-Hydroxysarmentogenin-3-O-α-l-rhamnoside, Trewianin, and Their Aglycons