1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Zhang Jiang Hi-Tech Park, Pudong, Shanghai 201203, P. R. China
2. University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, P. R. China
3. University of Nottingham Ningbo China, 199 Taikang East Road, Ningbo, Zhejiang 315100, P. R. China
4. GlaxoSmithKline, ELT/NCE Molecular Discovery, Medicinal Science & Technology, 200 Cambridge Park Drive, Cambridge, Massachusetts 02410, United States