Stereoselective Synthesis of the IDO Inhibitor Navoximod-Reference-Cited by-同舟云学术

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Stereoselective Synthesis of the IDO Inhibitor Navoximod

Published:2022-03-23 Issue:7 Volume:87 Page:4955-4960
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

St-Jean Frédéric¹^ORCID,Angelaud Rémy¹,Bachmann Stephan²,Carrera Diane E.¹,Remarchuk Travis¹,Piechowicz Katarzyna A.¹,Niedermann Katrin²,Iding Hans²,Meier Roland²,Hou Haiyun¹,Sirois Lauren E.¹^ORCID,Xu Jie¹^ORCID,Olbrich Martin²,Rege Pankaj²,Guillemot-Plass Maud²,Gosselin Francis¹^ORCID

Affiliation:

1. Department of Small Molecule Process Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States

2. Synthetic Molecules Technical Development, F. Hoffmann-La Roche Ltd., Grenzacherstraße 124, 4070 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.1c02994

Reference32 articles.

1. Why tumours eat tryptophan

2. Immune escape as a fundamental trait of cancer: focus on IDO

3. Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees?

4. IDO: more than an enzyme

5. Ido expression by dendritic cells: tolerance and tryptophan catabolism

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