Selection of Fragments for Kinase Inhibitor Design: Decoration Is Key-Reference-Cited by-同舟云学术

Selection of Fragments for Kinase Inhibitor Design: Decoration Is Key

Published:2014-12-12 Issue:1 Volume:58 Page:457-465
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Czodrowski Paul¹,Hölzemann Günter¹,Barnickel Gerhard¹,Greiner Hartmut¹,Musil Djordje¹

Affiliation:

1. Discovery Technologies, Merck Serono Research, Merck Serono R&D, Merck KGaA, Frankfurter Strasse 250, 64293 Darmstadt, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501597j

Reference31 articles.

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2. Hoelzemann, G.; Ackermann, K.A.; Crassier, H.; Jonczyk, A.; Rautenberg, W.; Tarrason, G.; Rosell-Vives, E.; Adan, J.; Cases, C.DE102004054215, 2006.

3. Role of the Active-Site Solvent in the Thermodynamics of Factor Xa Ligand Binding

4. Molecular Dynamics of Protein Kinase-Inhibitor Complexes: A Valid Structural Information

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