Asymmetric Synthesis of a TRPV1 Antagonist via tert-Butanesulfinamide-Directed Reductive Amination with a Chromanone
Author:
Affiliation:
1. Process Research and Development, AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064-1802, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op400184f
Reference19 articles.
1. Analgesic potential of TRPV1 antagonists
2. Transient receptor potential vanilloid-1 antagonists: a survey of recent patent literature
3. Vanilloid Receptor TRPV1 Antagonists as the Next Generation of Painkillers. Are We Putting the Cart before the Horse?
4. Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway
5. Pharmacology of Modality-Specific Transient Receptor Potential Vanilloid-1 Antagonists That Do Not Alter Body Temperature
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