Enhancing the Sensitivity of Pharmacophore-Based Virtual Screening by Incorporating Customized ZBG Features: A Case Study Using Histone Deacetylase 8-Reference-Cited by-同舟云学术

Enhancing the Sensitivity of Pharmacophore-Based Virtual Screening by Incorporating Customized ZBG Features: A Case Study Using Histone Deacetylase 8

Published:2015-03-16 Issue:4 Volume:55 Page:861-871
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Hou Xuben¹,Du Jintong²,Liu Renshuai¹,Zhou Yi¹,Li Minyong¹,Xu Wenfang¹,Fang Hao¹

Affiliation:

1. Department of Medicinal Chemistry, Key Laboratory of Chemical Biology of Natural Products (MOE), School of Pharmacy, Shandong University, Jinan, Shandong 250012, China

2. Shandong Cancer Hospital and Institute, Jinan, Shandong 250117, China

Funder

National Natural Science Foundation of China

Ministry of Education of the People's Republic of China

Program for New Century Excellent Talents in University

Shandong Natural Science Fund for Distinguished Young Scholars

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci500762z

Reference87 articles.

1. Cancer epigenetics reaches mainstream oncology

2. Epigenetic protein families: a new frontier for drug discovery

3. Histone acetylation in chromatin structure and transcription

4. Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

5. Acetylation and deacetylation of non-histone proteins

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