Novel Ester and Acid Derivatives of the 1,5-Diarylpyrrole Scaffold as Anti-Inflammatory and Analgesic Agents. Synthesis and in Vitro and in Vivo Biological Evaluation-Reference-Cited by-同舟云学术

Novel Ester and Acid Derivatives of the 1,5-Diarylpyrrole Scaffold as Anti-Inflammatory and Analgesic Agents. Synthesis and in Vitro and in Vivo Biological Evaluation

Published:2009-12-03 Issue:2 Volume:53 Page:723-733
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Biava Mariangela¹,Porretta Giulio C.¹,Poce Giovanna¹,Battilocchio Claudio¹,Manetti Fabrizio²,Botta Maurizio²,Forli Stefano²,Sautebin Lidia³,Rossi Antonietta⁴,Pergola Carlo³,Ghelardini Carla⁵,Galeotti Nicoletta⁵,Makovec Francesco⁶,Giordani Antonio⁶,Anzellotti Paola⁷,Patrignani Paola⁷,Anzini Maurizio²⁸

Affiliation:

1. Dipartimento di Studi di Chimica e Tecnologie del Farmaco, Università “La Sapienza”, piazzale Aldo Moro 5, I-00185 Roma, Italy

2. Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, via Alcide de Gasperi 2, I-53100 Siena, Italy

3. Dipartimento di Farmacologia Sperimentale, Università di Napoli “Federico II”, via D. Montesano 49, I-80131 Napoli, Italy

4. IRCCS Centro Neurolesi “Bonino-Pulejo”, via Provinciale Palermo, C. da Casazza, I-98124 Messina, Italy

5. Dipartimento di Farmacologia, Università di Firenze, viale G. Pieraccini 6, I-50139 Firenze, Italy

6. Rottapharm SpA, via Valosa di Sopra 7, I-20052 Monza, Italy

7. Department of Medicine and Center of Excellence on Aging, “G. d’Annunzio” University and CeSI, Via dei Vestini 31, I-66013 Chieti, Italy

8. European Research Centre for Drug Discovery and Development, via Banchi di Sotto 55, I-53100 Siena, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901269y

Reference41 articles.

1. The Coxibs, Selective Inhibitors of Cyclooxygenase-2

2. Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis

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4. Marked Interindividual Variability in the Response to Selective Inhibitors of Cyclooxygenase-2

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