Synthesis and Biological Evaluation of Novel Sigma-1 Receptor Antagonists Based on Pyrimidine Scaffold As Agents for Treating Neuropathic Pain-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of Novel Sigma-1 Receptor Antagonists Based on Pyrimidine Scaffold As Agents for Treating Neuropathic Pain

Published:2014-12-04 Issue:24 Volume:57 Page:10404-10423
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lan Yu¹,Chen Yin²,Cao Xudong¹,Zhang Juecheng¹,Wang Jie¹,Xu Xiangqing²,Qiu Yinli²,Zhang Tan²,Liu Xin¹,Liu Bi-Feng¹,Zhang Guisen¹²

Affiliation:

1. Systems Biology Theme, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China

2. Jiangsu Nhwa Pharmaceutical Co., Ltd., 69 Democratic South Road, Xuzhou, Jiangsu 221116, China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501207r

Reference72 articles.

1. Neuropathic pain in the general population: A systematic review of epidemiological studies

2. Emerging drugs for neuropathic pain

3. Neuropathic Pain and Pharmacological Treatment

4. Pharmacologic management of neuropathic pain: Evidence-based recommendations

5. EFNS guidelines on pharmacological treatment of neuropathic pain

Cited by 44 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The proof of concept of 2-{3-[N-(1-benzylpiperidin-4-yl)propyl]amino}-6-[N-methyl-N-(prop-2-yn-1-yl)amino]-4-phenylpyridine-3,5-dicarbonitrile for the therapy of neuropathic pain;Bioorganic Chemistry;2024-09

2. Computational studies of pyrimidine derivatives as inhibitors of human σ1 receptor using 3D-QSAR analysis, molecular docking, ADMET properties and DFT investigation;Chemical Physics Impact;2024-06

3. Molecular Imaging of Alzheimer’s Disease-Related Sigma-1 Receptor in the Brain via a Novel Ru-Mediated Aromatic ¹⁸F-deoxyfluorination Probe;Journal of Medicinal Chemistry;2024-04-12

4. Investigation into a Tetrahydroquinazoline Scaffold;European Journal of Organic Chemistry;2024-02-02

5. Recent Synthetic and Biological Developments on 1,2,4‐Triazolopyrimidines;ChemistrySelect;2023-09-04