Molecular Imaging of Alzheimer’s Disease-Related Sigma-1 Receptor in the Brain via a Novel Ru-Mediated Aromatic 18F-deoxyfluorination Probe

Author:

Bai Ping12345ORCID,Bagdasarian Frederick A.6,Xu Yulong6ORCID,Wang Yanli6,Wang Yongle6,Gomm Ashley7,Zhou Yanting12345,Wu Rui12345,Wey Hsiao-Ying6ORCID,Tanzi Rudolph E.7,Zhang Can7ORCID,Lan Yu8,Wang Changning6ORCID

Affiliation:

1. Department of Respiratory and Critical Care Medicine, Targeted Tracer Research and Development Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

2. Institute of Respiratory Health, Targeted Tracer Research and Development Laboratory, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

3. Precision Medicine Center, Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

4. The Research Units of West China, Chinese Academy of Medical Sciences, West China Hospital, Chengdu, Sichuan 610041, China

5. State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Chengdu, Sichuan 610041, China

6. Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, United States

7. Genetics and Aging Research Unit, McCance Center for Brain Health, MassGeneral Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States

8. Department of Pharmacy, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China

Publisher

American Chemical Society (ACS)

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