Improving the Editing Efficiency of CRISPR-Cas9 by Reducing the Generation of Escapers Based on the Surviving Mechanism-Reference-Cited by-同舟云学术

Improving the Editing Efficiency of CRISPR-Cas9 by Reducing the Generation of Escapers Based on the Surviving Mechanism

Published:2023-03-03 Issue:3 Volume:12 Page:672-680
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Li Qi¹,Sun Mingjun¹,Lv Lu¹,Zuo Yong¹,Zhang Suyi²,Zhang Ying³,Yang Sheng⁴⁵^ORCID

Affiliation:

1. College of Life Sciences, Sichuan Normal University, Chengdu 610101, China

2. Luzhou Laojiao Co., Ltd, Luzhou 646000, Sichuan China

3. BBSRC/EPSRC Synthetic Biology Research Centre (SBRC), Biodiscovery Institute, School of Life Sciences, The University of Nottingham, Nottingham NG7 2RD, United Kingdom

4. Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 200032, China

5. Huzhou Center of Industrial Biotechnology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Huzhou 313000, China

Funder

Department of Science and Technology of Sichuan Province

Chinese Academy of Sciences

Luzhou Laojiao Co., Ltd

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acssynbio.2c00619

Reference54 articles.

1. CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

2. Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes

3. CRISPR/Cas, the Immune System of Bacteria and Archaea

4. Multiplex Genome Engineering Using CRISPR/Cas Systems

5. Development and Applications of CRISPR-Cas9 for Genome Engineering

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