Directed Evolution of Stabilized Monomeric CD19 for Monovalent CAR Interaction Studies and Monitoring of CAR-T Cell Patients-Reference-Cited by-同舟云学术

Directed Evolution of Stabilized Monomeric CD19 for Monovalent CAR Interaction Studies and Monitoring of CAR-T Cell Patients

Published:2021-04-12 Issue:5 Volume:10 Page:1184-1198
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Laurent Elisabeth¹^ORCID,Sieber Anna²,Salzer Benjamin³,Wachernig Anna²,Seigner Jacqueline⁴,Lehner Manfred³,Geyeregger René³,Kratzer Bernhard⁵,Jäger Ulrich⁶,Kunert Renate²,Pickl Winfried F.⁵,Traxlmayr Michael W.⁴

Affiliation:

1. Department of Biotechnology and BOKU Core Facility Biomolecular and Cellular Analysis, BOKU - University of Natural Resources and Life Sciences, Muthgasse 18, 1190 Vienna, Austria

2. Department of Biotechnology, BOKU - University of Natural Resources and Life Sciences, Muthgasse 18, 1190 Vienna, Austria

3. St. Anna Children’s Cancer Research Institute, Zimmermannplatz 10, 1090 Vienna, Austria

4. Department of Chemistry, BOKU - University of Natural Resources and Life Sciences, Muthgasse 18, 1190 Vienna, Austria

5. Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Lazarettgasse 19, 1090 Vienna, Austria

6. Department of Internal Medicine, Division of Hematology and Hemostaseology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria

Funder

Austrian Science Fund

Children’s Cancer Research Institute

Platform for advanced cellular therapies (PACT)

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acssynbio.1c00010

Reference62 articles.

1. Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia