The CRISPR-Cas12a Platform for Accurate Genome Editing, Gene Disruption, and Efficient Transgene Integration in Human Immune Cells
Author:
Affiliation:
1. Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet 220, 2800 Kongens Lyngby, Denmark
2. Artisan Bio, 363 Centennial Parkway, Suite 310, Louisville, Colorado 80027, United States
Funder
Novo Nordisk Fonden
Publisher
American Chemical Society (ACS)
Subject
Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acssynbio.2c00179
Reference48 articles.
1. The promise and challenge of therapeutic genome editing
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4. Optimization of AsCas12a for combinatorial genetic screens in human cells
5. A more efficient CRISPR-Cas12a variant derived from Lachnospiraceae bacterium MA2020
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