Indirubin Core Structure of Glycogen Synthase Kinase-3 Inhibitors as Novel Chemotype for Intervention with 5-Lipoxygenase-Reference-Cited by-同舟云学术

Indirubin Core Structure of Glycogen Synthase Kinase-3 Inhibitors as Novel Chemotype for Intervention with 5-Lipoxygenase

Published:2014-04-17 Issue:9 Volume:57 Page:3715-3723
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pergola Carlo¹,Gaboriaud-Kolar Nicolas²,Jestädt Nadine¹,König Stefanie¹,Kritsanida Marina²,Schaible Anja M.¹,Li Haokun¹,Garscha Ulrike¹,Weinigel Christina,Barz Dagmar,Albring Kai F.,Huber Otmar,Skaltsounis Alexios L.²,Werz Oliver¹

Affiliation:

1. Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University, Jena 07743, Germany

2. Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, University of Athens, Athens 15771, Greece

Funder

European Commission

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401740w

Reference38 articles.

1. 5-Lipoxygenase: regulation of expression and enzyme activity

2. Leukotrienes

3. Targeting leukotriene B4in inflammation

4. 5-Lipoxygenase inhibitors: a review of recent developments and patents

5. Novel and Potent Inhibitors of 5-Lipoxygenase Product Synthesis Based on the Structure of Pirinixic Acid

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