Enantioselective Synthesis of β-Trifluoromethyl α-Amino Acids
Author:
Affiliation:
1. Wyeth Research, 1025 Marcel-Laurin Boulevard, St-Laurent, Québec H4R 1J6, Canada
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol100478d
Reference26 articles.
1. Synthesis of α-Trifluoromethyl-β-lactams and Esters of β-Amino Acids via 1,3-Dipolar Cycloaddition of Nitrones to Fluoroalkenes
2. Helix Propensity of Highly Fluorinated Amino Acids
3. Synthesis of optically pure (R)- and (S)-α-trifluoromethyl-alanine
4. Asymmetric reduction of 2-(N-arylimino)-3,3,3-trifluoropropanoic acid esters leading to enantiomerically enriched 3,3,3-trifluoroalanine
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