Enantio- and Diastereoselective Total Synthesis of Belzutifan Enabled by Rh-Catalyzed Hydrogenation-Reference-Cited by-同舟云学术

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Enantio- and Diastereoselective Total Synthesis of Belzutifan Enabled by Rh-Catalyzed Hydrogenation

Published:2024-05-06 Issue:19 Volume:26 Page:4059-4064
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Le Diane N.¹^ORCID,Johnson Heather C.¹^ORCID,Lam Yu-hong²^ORCID,Sun Chunrui¹,Cheng Lili³,Belyk Kevin M.¹^ORCID

Affiliation:

1. Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States

2. Modeling and Informatics, Merck & Co., Inc., Rahway, New Jersey 07065, United States

3. Chemistry Service Unit, WuXi AppTec (Tianjin), Tianjin 300457, China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.4c00982

Reference46 articles.

1. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

2. Epidemiology and Clinicopathological Profile of Renal Cell Carcinoma: A Review from Tertiary Care Referral Centre

3. HIF Transcription Factors, Inflammation, and Immunity

4. HIF-2α Promotes Hypoxic Cell Proliferation by Enhancing c-Myc Transcriptional Activity

5. Current and emerging therapies for first-line treatment of metastatic clear cell renal cell carcinoma

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