Synthesis and Biological Activity of a New Series of N6-Arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-Carboxamido Derivatives of Adenosine-5‘-N-ethyluronamide as A1 and A3 Adenosine Receptor Agonists-Reference-Cited by-同舟云学术

Synthesis and Biological Activity of a New Series of N6-Arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-Carboxamido Derivatives of Adenosine-5‘-N-ethyluronamide as A1 and A3 Adenosine Receptor Agonists

Published:1998-07-22 Issue:17 Volume:41 Page:3174-3185
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Baraldi Pier Giovanni¹,Cacciari Barbara¹,Pineda de Las Infantas Maria José¹,Romagnoli Romeo¹,Spalluto Giampiero¹,Volpini Rosaria¹,Costanzi Stefano¹,Vittori Sauro¹,Cristalli Gloria¹,Melman Neli¹,Park Kyung-Sun¹,Ji Xiao-duo¹,Jacobson Kenneth A.¹

Affiliation:

1. Dipartimento di Scienze Farmaceutiche, Università di Ferrara, Via Fossato di Mortara 17-19, 44100 Ferrara, Italy, Dipartimento di Scienze Chimiche, Università di Camerino, Via S. Agostino 1, 62032 Camerino, Italy, and Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm980147p

Reference63 articles.

1. The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor.

2. RDC8 codes for an adenosine A2 receptor with physiological constitutive activity

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