Synthesis and anticancer activity of multisubstituted purines and xanthines with one or two propynylthio and aminobutynylthio groups

Author:

Kowalska Alicja,Pluta Krystian,Latocha Małgorzata

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics

Reference37 articles.

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2. Atamanyuk D, Denis A, Gerusz V, Ledoussal B, Bonvin Y, Desroy N, Gold J, Moreau F, Oxoby M (2012) Purine derivatives and their use as pharmaceuticals for prevention or treatment of bacterial infections. European Patent WO2012172043 (A1)

3. Baraldi PG, Cacciari B, de Las Infantas MJP, Romagnoli R, Spalluto G, Volpini R, Costanzi S, Vittori S, Cristalli G, Melman N, Park KS, Ji X, Jacobson KA (1998) Synthesis and biological activity of a new series of N6-arylcarbamoyl, 2-(Ar)alkynyl- N6-arylcarbamoyl, and N6-carboxamido derivatives of adenosine-5’-N-ethyluronamide as A1 and A3 adenosine receptor agonists. J Med Chem 41:3174–3185

4. Berg TC, Gundersen LL, Eriksen AB, Malterud KE (2005) Synthesis of optically active 6-alkynyl- and 6-alkylpurines as cytokinin analogs and inhibitors of 15-lipoxygenase; studes of intramolecular cyclization of 6-(hydroxyalkyn-1-yl)purines. J Org Chem 23:4988–4994

5. Bliman D, Pettersson M, Bood M, Grotli M (2014) 8-Bromination of 2,6,9-trisubstituted purines with pyridinium tribromide. Tetrahedron Lett 55:2929–2931

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