Stereoselective Synthesis of New Conformationally Restricted Analogues of a Potent CGRP Receptor Antagonist-Reference-Cited by-同舟云学术

Stereoselective Synthesis of New Conformationally Restricted Analogues of a Potent CGRP Receptor Antagonist

Published:2005-05-17 Issue:12 Volume:7 Page:2465-2468
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Zuev Dmitry¹,Michne Jodi A.¹,Huang Hong¹,Beno Brett R.¹,Wu Dedong¹,Gao Qi¹,Torrente John R.¹,Xu Cen¹,Conway Charles M.¹,Macor John E.¹,Dubowchik Gene M.¹

Affiliation:

1. Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 5100, Wallingford, Connecticut 06492

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol0510062

Reference16 articles.

1. CONFORMATIONAL RESTRICTION AND/OR STERIC HINDRANCE IN MEDICINAL CHEMISTRY

2. RING TRANSFORMATIONS

3. Characterisation of the effects of a non-peptide CGRP receptor antagonist in SK-N-MC cells and isolated human cerebral arteries

4. Synthesis of lactam and ketone precursors of 2,7-substituted octahydro-pyrrolo[1,2-a]pyrazines and octahydro-2H-pyrido[1,2-a]pyrazines

5. Synthesis and 2,7-functionalization of the bicyclic lactam 2-benzyloctahydropyrido[1,2-a]pyrazin-6-one

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