Programmable iodization/deuterolysis sequences of phosphonium ylides to access deuterated benzyl iodides and aromatic aldehydes-Reference-Cited by-同舟云学术

Programmable iodization/deuterolysis sequences of phosphonium ylides to access deuterated benzyl iodides and aromatic aldehydes

Published:2022 Issue:26 Volume:58 Page:4215-4218
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Zheng Yu¹,He Xian-Chen¹,Gao Jie¹,Xie Zhen-Zhen¹,Wang Zhi-Wei¹,Liu Zhi-Lin¹,Chen Kai¹^ORCID,Xiang Hao-Yue¹²^ORCID,Chen Xiao-Qing¹^ORCID,Yang Hua¹^ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, P. R. China

2. School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, Henan, P. R. China

Abstract

Herein, a tunable iodization/deuterolysis protocol for phosphonium ylides by employing D2O as the deuterium source was designed.

Funder

Natural Science Foundation of Hunan Province

National Natural Science Foundation of China

Henan Normal University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D2CC00537A

Reference48 articles.

1. Applications of Deuterium in Medicinal Chemistry

2. Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences

3. Isotope chemistry; a useful tool in the drug discovery arsenal

4. The Deuterium Isotope Effect

5. Deuterated drugs; updates and obviousness analysis

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