Role of Surface Exposed Tryptophan as Substrate Generators for the Antibody Catalyzed Water Oxidation Pathway
Author:
Affiliation:
1. Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, Kansas 66047, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/mp300418r
Reference47 articles.
1. Identification of a Single Tryptophan Residue as Critical for Binding Activity in a Humanized Monoclonal Antibody against Respiratory Syncytial Virus
2. Characterization of the photodegradation of a human IgG1 monoclonal antibody formulated as a high-concentration liquid dosage form
3. Photosensitizers Form in Histidine Buffer and Mediate the Photodegradation of a Monoclonal Antibody
4. Antibodies have the intrinsic capacity to destroy antigens
5. Immunoglobulins can utilize riboflavin (Vitamin B2) to activate the antibody-catalyzed water oxidation pathway
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