1. Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, Instituto de Investigaciones Científicas y Servicios de Alta Tecnología, Ciudad del Saber, Clayton, 0843-01103 Panamá, and Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104 Freiburg, Germany