1. Department of Medicinal Chemistry II, Medicinal Chemistry Research, H. Lundbeck A/S, 9 Ottiliavej, DK, 2500 Valby, Denmark, LifeCycle Pharma, 3 Kogle Alle, DK, 2730 Hoersholm, Denmark, and Synaptic Pharmaceutical Corporation, 215 College Road, Paramus, New Jersey 07652