Synthesis and Evaluation of Novel α-Fluorinated (E)-3-((6-Methylpyridin-2-yl)ethynyl)cyclohex-2-enone-O-methyl Oxime (ABP688) Derivatives as Metabotropic Glutamate Receptor Subtype 5 PET Radiotracers-Reference-Cited by-同舟云学术

Synthesis and Evaluation of Novel α-Fluorinated (E)-3-((6-Methylpyridin-2-yl)ethynyl)cyclohex-2-enone-O-methyl Oxime (ABP688) Derivatives as Metabotropic Glutamate Receptor Subtype 5 PET Radiotracers

Published:2012-08-09 Issue:16 Volume:55 Page:7154-7162
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Milicevic Sephton Selena¹,Mu Linjing¹,Schweizer W. Bernd²,Schibli Roger¹,Krämer Stefanie D.¹,Ametamey Simon M.¹

Affiliation:

1. Center for Radiopharmaceutical Sciences of ETH, PSI and USZ, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH) Zurich, Wolfgang-Pauli Strasse 10, 8093, Zurich, Switzerland

2. Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH) Zurich, Wolfgang-Pauli Strasse 10, 8093 Zurich, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300648b

Reference66 articles.

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3. Radioligands for the PET Imaging of Metabotropic Glutamate Receptor Subtype 5 (mGluR5)

4. The metabotropic glutamate receptors: Structure and functions

5. Differential Presynaptic Localization of Metabotropic Glutamate Receptor Subtypes in the Rat Hippocampus

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