Synthesis of a Nucleoside Phosphoramidate Prodrug Inhibitor of HCV NS5B Polymerase: Phenylboronate as a Transient Protecting Group-Reference-Cited by-同舟云学术

Synthesis of a Nucleoside Phosphoramidate Prodrug Inhibitor of HCV NS5B Polymerase: Phenylboronate as a Transient Protecting Group

Published:2014-05-21 Issue:6 Volume:18 Page:717-724
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Mayes Benjamin A.¹,Arumugasamy Jeevanandam¹,Baloglu Erkan¹,Bauer David¹,Becker Alan¹,Chaudhuri Narayan¹,Latham G. Mark¹,Li Jie¹,Mathieu Steve¹,McGarry F. Patrick¹,Rosinovsky Elodie¹,Stewart Alistair¹,Trochet Christophe¹,Wang Jingyang¹,Moussa Adel¹

Affiliation:

1. Idenix Pharmaceuticals Inc., 320 Bent Street, Cambridge, Massachusetts 02141, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op500042u

Reference35 articles.

1. New therapies for chronic hepatitis C infection: a systematic review of evidence from clinical trials

2. Global epidemiology of hepatitis C virus infection

3. Directly acting antivirals for the treatment of patients with hepatitis C infection: A clinical development update addressing key future challenges

4. Phosphoramidate Prodrugs of 2′-C-Methylcytidine for Therapy of Hepatitis C Virus Infection

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