Phosphoramidate Prodrugs of 2′-C-Methylcytidine for Therapy of Hepatitis C Virus Infection-Reference-Cited by-同舟云学术

Phosphoramidate Prodrugs of 2′-C-Methylcytidine for Therapy of Hepatitis C Virus Infection

Published:2009-08-06 Issue:17 Volume:52 Page:5394-5407
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gardelli Cristina¹,Attenni Barbara¹,Donghi Monica¹,Meppen Malte¹,Pacini Barbara¹,Harper Steven¹,Di Marco Annalise¹,Fiore Fabrizio¹,Giuliano Claudio¹,Pucci Vincenzo¹,Laufer Ralph¹,Gennari Nadia¹,Marcucci Isabella¹,Leone Joseph F.²,Olsen David B.³,MacCoss Malcolm²,Rowley Michael¹,Narjes Frank¹

Affiliation:

1. Departments of Medicinal Chemistry and Pharmacology, Istituto di Ricerche di Biologia Molecolare, P. Angeletti S.p.A. (IRBM-MRL Rome), Via Pontina Km 30,600, 00040 Pomezia, Italy

2. Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, New Jersey 07065

3. Department of Antiviral Research, Merck Research Laboratories, West Point, Pennsylvania 19486

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900447q

Reference47 articles.

1. Global epidemiology of hepatitis C virus infection

2. Antiviral therapy for chronic hepatitis C: past, present, and future

3. Mechanisms of antiviral treatment efficacy and failure in chronic hepatitis C

4. Directly acting antivirals for the treatment of patients with hepatitis C infection: A clinical development update addressing key future challenges

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