Synthesis and Evaluation of 2,6-Modified Purine 2′-C-Methyl Ribonucleosides as Inhibitors of HCV Replication-Reference-Cited by-同舟云学术

Synthesis and Evaluation of 2,6-Modified Purine 2′-C-Methyl Ribonucleosides as Inhibitors of HCV Replication

Published:2015-12-04 Issue:1 Volume:7 Page:17-22
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Zhou Longhu¹,Zhang Hongwang¹,Tao Sijia¹,Ehteshami Maryam¹,Cho Jong Hyun¹,McBrayer Tamara R.²,Tharnish Philip²,Whitaker Tony²,Amblard Franck¹,Coats Steven J.²,Schinazi Raymond F.¹

Affiliation:

1. Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, and Veterans Affairs Medical Center, Atlanta, Georgia 30322, United States

2. CoCrystal Pharma, Inc., Tucker, Georgia 30084, United States

Funder

U.S. Department of Veterans Affairs

National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.5b00402

Reference21 articles.

1. Challenges and successes in developing new therapies for hepatitis C