Discovery of a β-d-2′-Deoxy-2′-α-fluoro-2′-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus-Reference-Cited by-同舟云学术

Discovery of a β-d-2′-Deoxy-2′-α-fluoro-2′-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus

Published:2010-09-16 Issue:19 Volume:53 Page:7202-7218
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sofia Michael J.¹,Bao Donghui¹,Chang Wonsuk¹,Du Jinfa¹,Nagarathnam Dhanapalan¹,Rachakonda Suguna¹,Reddy P. Ganapati¹,Ross Bruce S.¹,Wang Peiyuan¹,Zhang Hai-Ren¹,Bansal Shalini¹,Espiritu Christine¹,Keilman Meg¹,Lam Angela M.¹,Steuer Holly M. Micolochick¹,Niu Congrong¹,Otto Michael J.¹,Furman Phillip A.¹

Affiliation:

1. Pharmasset, Inc., 303A College Road East, Princeton, New Jersey 08540

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100863x

Reference43 articles.

1. The global burden of hepatitis C

2. Expert opinion on the treatment of patients with chronic hepatitis C

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4. HCV NS5B Polymerase Inhibitors

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